Ubiquitin (UB) is a protein modifier that regulates many essential cellular processes. To initiate protein modification by UB, the E1 enzyme activates the C-terminal carboxylate of UB to launch its transfer through the E1-E2-E3 cascade onto target proteins. The E1 enzyme is the activating enzyme, to which ubiquitin is attached in an ATP-dependent reaction by a thioester bond. The E2 enzyme is the conjugating enzyme, to which the ubiquitin is transferred from the E1. The E3 is the ubiquitin ligase, which directly or indirectly catalyzes the transfer of the ubiquitin to the target protein (the substrate), with the formation of an isopeptide bond.
BD4907002096333-48-997%
￥暂无
BD559121675576-98-499%
￥1023.005mg
BD629686803647-40-798+%
￥1116.005mg
BD6298151002789-86-798+%
￥602.001mg
BD6301011303607-60-498+%
￥2344.0010mg
BD6301081309684-94-398+%
￥2462.0025mg
BD6301211319207-44-798+%
￥8476.005mg
BD6301681352066-68-298+%
￥639.001mg
BD234849939983-14-998+%
￥13320.00100mg
BD165438939981-37-098+%
￥18600.00100mg
BD63063131083-55-398+%
￥419.005mg
BD630703431979-47-498+%
￥1256.0010mg
BD24252519542-67-798+%
￥572.00100mg
BD305810418805-02-498+%
￥571.005mg
BD5000485532-75-897%
￥暂无
BD755822548472-68-099+%
￥1209.0010mg
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