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ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine kinases. ROCKs (ROCK1 and ROCK2) occur in mammals, zebrafish, Xenopus, invertebrates and chicken. Human ROCK1 has a molecular mass of 158 kDa and is a major downstream effector of the small GTPase RhoA. Mammalian ROCK consists of a kinase domain, acoiled-coil region and a Pleckstrin homology (PH) domain, which reduces the kinase activity of ROCKs by an autoinhibitory intramolecular fold if RhoA-GTP is not present. ROCK plays a role in a wide range of different cellular phenomena, as ROCK is a downstream effector protein of the small GTPase Rho, which is one of the major regulators of the cytoskeleton.

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2096333-48-9

BD4907002096333-48-997%

¥暂无

1342276-76-9

BD3290811342276-76-995+%

¥2652.0025mg

1072959-67-1

BD5591621072959-67-198+%

¥6138.00100mg

105628-72-6

BD55242105628-72-698+%

¥795.0010mg

911417-87-3

BD448309911417-87-398+%

¥1000.0010mg

129830-38-2

BD292959129830-38-299+%

¥8184.00250mg

1226056-71-8

BD1598501226056-71-898+%

¥1302.0010mg

105628-07-7

BD130021105628-07-798+%

¥103.00250mg

1273579-40-0

BD6300851273579-40-098+%

¥2474.005mg

923262-96-8

BD316131923262-96-898+%

¥5487.0050mg

199433-58-4

BD630514199433-58-498+%

¥1400.005mg

155558-32-0

BD305625155558-32-098+%

¥650.005mg

871543-07-6

BD306018871543-07-698+%

¥3027.0010mg

2095432-71-4

BD7648422095432-71-498+%

¥1966.0025mg

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